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[13C]bicarbonate labelled from hyperpolarized [1-13C]pyruvate is an in vivo marker of hepatic gluconeogenesis in fasted state
Can et al. demonstrate the ability to use hyperpolarized [1-13C]pyruvate at nearphysiological concentrations to directly assess liver enzymatic activities by 13C magnetic resonance. While in the fed state, the normalized [13C]bicarbonate signal produced from hyperpolarized [1-13C]pyruvate derives fr...
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| Udgivet i: | Communications Biology |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Udgivet: |
Nature Portfolio
2022-01-01
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| Online adgang: | https://doi.org/10.1038/s42003-021-02978-2 |
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