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Rifampin Concentrations in Various Compartments of the Human Brain: A Novel Method for Determining Drug Levels in the Cerebral Extracellular Space

Antimicrobial therapy for brain infections is notoriously difficult because of the limited extent of knowledge about drug penetration into the brain. Therefore, we determined the penetration of rifampin into various compartments of the human brain, including the cerebral extracellular space (CES). P...

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Hlavní autoři: Mindermann, Thomas, Zimmerli, Werner, Gratzl, Otmar
Médium: Článek
Jazyk:en
Vydáno: American Society for Microbiology 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC105908/
https://ncbi.nlm.nih.gov/pubmed/9756766
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