Single photon emission computed tomography in long-term survivors of adult brain tumours.

Sixteen patients with primary brain tumours were examined on average eight years after treatment with surgery or whole brain irradiation using standard clinical assessment, CT, a neuropsychological test battery, and single photon emission CT (SPECT) with 99mTc-exametazime. Seventeen lesions were dis...

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Main Authors: Ebmeier, K P, Booker, K, Gregor, A, Cull, A, Dougall, N, Sellar, R, Goodwin, G M
Format: Artigo
Sprog:English
Udgivet: 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1072978/
https://ncbi.nlm.nih.gov/pubmed/8006655
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spelling pubmed-10729782008-04-11 Single photon emission computed tomography in long-term survivors of adult brain tumours. Ebmeier, K P Booker, K Gregor, A Cull, A Dougall, N Sellar, R Goodwin, G M J Neurol Neurosurg Psychiatry Research Article Sixteen patients with primary brain tumours were examined on average eight years after treatment with surgery or whole brain irradiation using standard clinical assessment, CT, a neuropsychological test battery, and single photon emission CT (SPECT) with 99mTc-exametazime. Seventeen lesions were discovered on inspection of SPECT images, 11 with x-ray CT. Quantitative assessment of tracer uptake compared with 16 matched healthy volunteers was consistent with the presence of lesions. Measurement of uptake in brain regions of the hemisphere not containing the primary tumour still showed significant reductions in patients. This may be due to remote direct effects of the tumour or, more likely, to the whole brain irradiation received. Psychometric performance on most tests was significantly impaired in the patient group and was correlated with abnormalities of tracer uptake to relevant brain regions. 1994-06 /pmc/articles/PMC1072978/ /pubmed/8006655 Text en
institution US National Library of Medicine
collection PubMed Central
language English
format Article
topic Research Article
spellingShingle Research Article
Ebmeier, K P
Booker, K
Gregor, A
Cull, A
Dougall, N
Sellar, R
Goodwin, G M
Single photon emission computed tomography in long-term survivors of adult brain tumours.
description Sixteen patients with primary brain tumours were examined on average eight years after treatment with surgery or whole brain irradiation using standard clinical assessment, CT, a neuropsychological test battery, and single photon emission CT (SPECT) with 99mTc-exametazime. Seventeen lesions were discovered on inspection of SPECT images, 11 with x-ray CT. Quantitative assessment of tracer uptake compared with 16 matched healthy volunteers was consistent with the presence of lesions. Measurement of uptake in brain regions of the hemisphere not containing the primary tumour still showed significant reductions in patients. This may be due to remote direct effects of the tumour or, more likely, to the whole brain irradiation received. Psychometric performance on most tests was significantly impaired in the patient group and was correlated with abnormalities of tracer uptake to relevant brain regions.
author Ebmeier, K P
Booker, K
Gregor, A
Cull, A
Dougall, N
Sellar, R
Goodwin, G M
author_facet Ebmeier, K P
Booker, K
Gregor, A
Cull, A
Dougall, N
Sellar, R
Goodwin, G M
author_sort Ebmeier, K P
title Single photon emission computed tomography in long-term survivors of adult brain tumours.
title_short Single photon emission computed tomography in long-term survivors of adult brain tumours.
title_full Single photon emission computed tomography in long-term survivors of adult brain tumours.
title_fullStr Single photon emission computed tomography in long-term survivors of adult brain tumours.
title_full_unstemmed Single photon emission computed tomography in long-term survivors of adult brain tumours.
title_sort single photon emission computed tomography in long-term survivors of adult brain tumours.
publishDate 1994
url https://ncbi.nlm.nih.gov/pmc/articles/PMC1072978/
https://ncbi.nlm.nih.gov/pubmed/8006655
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