Mutations in Rotavirus Nonstructural Glycoprotein NSP4 Are Associated with Altered Virus Virulence

Rotaviruses are major pathogens causing life-threatening dehydrating gastroenteritis in children and animals. One of the nonstructural proteins, NSP4 (encoded by gene 10), is a transmembrane, endoplasmic reticulum-specific glycoprotein. Recently, our laboratory has shown that NSP4 causes diarrhea in...

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Autors principals: Zhang, Mingdong, Zeng, Carl Q.-Y., Dong, Yanjie, Ball, Judith M., Saif, Linda J., Morris, Andrew P., Estes, Mary K.
Format: Article
Idioma:en
Publicat: American Society for Microbiology 1998
Matèries:
Viral Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC109587/
https://ncbi.nlm.nih.gov/pubmed/9557647
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https://ncbi.nlm.nih.gov/pmc/articles/PMC109587/
https://ncbi.nlm.nih.gov/pubmed/9557647

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