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Naturally Occurring Mutations Define a Novel Function of the Hepatitis B Virus Core Promoter in Core Protein Expression

Functional analysis of naturally occurring hepatitis B virus (HBV) mutations is crucial in understanding their impact on disease. We have recently identified two mutations in the HBV core promoter of an HBV strain associated with fulminant hepatitis leading to highly (15-fold) enhanced replication a...

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Autores principales: Baumert, Thomas F., Marrone, Aldo, Vergalla, John, Liang, T. Jake
Formato: Artículo
Lenguaje:en
Publicado: American Society for Microbiology 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC109887/
https://ncbi.nlm.nih.gov/pubmed/9658127
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