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RGD Inclusion in the Hexon Monomer Provides Adenovirus Type 5-Based Vectors with a Fiber Knob-Independent Pathway for Infection
Hypervariable region 5 (HVR5) is a hydrophilic, serotypically nonconserved loop of the hexon monomer which extrudes from the adenovirus (Ad) capsid. We have replaced the HVR5 sequence of Ad5 with that of heterologous peptides and studied their effects on virus viability and peptide accessibility. A...
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| Автори: | , , , , , |
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| Формат: | Стаття |
| Мова: | en |
| Опубліковано: |
American Society for Microbiology
1999
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.gov/pmc/articles/PMC112562/ https://ncbi.nlm.nih.gov/pubmed/10233980 |
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