TY  - JOUR
T1  - Persistence of Human Immunodeficiency Virus Type 1-Specific Cytotoxic T-Lymphocyte Clones in a Subject with Rapid Disease Progression
A1  - Islam, Sabina A.
LA  - en
PB  - American Society for Microbiology
YR  - 2001
UL  - http://buscaintegrada.pucsp.br/vufind/Record/pubmed-114246
AB  - We longitudinally measured T-cell receptor transcript frequencies of human immunodeficiency virus type 1 (HIV-1) specific cytotoxic T lymphocytes (CTL) in an individual with rapidly progressive disease and high levels of viremia. CTL clones elicited during acute HIV-1 infection were present at the time of death, despite absent functional CTL responses, arguing against clonal deletion as a mechanism for the decline of CTL responses observed during HIV-1 infection.
KW  - Pathogenesis and Immunity
ER  -