A Novel Nonnucleoside Inhibitor Specifically Targets Cytomegalovirus DNA Maturation via the UL89 and UL56 Gene Products

3-Hydroxy-2,2-dimethyl-N-[4({[5-(dimethylamino)-1-naphthyl]sulfonyl}amino)-phenyl]propanamide (BAY 38-4766) is a novel selective nonnucleoside inhibitor of cytomegalovirus (CMV) replication with an excellent safety profile. This compound and structural analogues inhibit neither viral DNA synthesis n...

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Bibliografiska uppgifter
Huvudupphovsmän: Buerger, Iris, Reefschlaeger, Juergen, Bender, Wolfgang, Eckenberg, Peter, Popp, Andreas, Weber, Olaf, Graeper, Sascha, Klenk, Hans-Dieter, Ruebsamen-Waigmann, Helga, Hallenberger, Sabine
Materialtyp: Artikel
Språk:en
Publicerad: American Society for Microbiology 2001
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC114476/
https://ncbi.nlm.nih.gov/pubmed/11533171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.19.9077-9086.2001
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC114476/
https://ncbi.nlm.nih.gov/pubmed/11533171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.19.9077-9086.2001

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