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A Novel CD8-Independent High-Avidity Cytotoxic T-Lymphocyte Response Directed against an Epitope in the Phosphoprotein of the Paramyxovirus Simian Virus 5
Adoptive transfer studies have shown that cytotoxic T lymphocytes (CTL) of high avidity, capable of recognizing low levels of peptide-MHC I molecules, are more efficient at reducing viral titers than are low-avidity CTL, thus establishing CTL avidity as a critical parameter for the ability of a CTL...
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| Format: | Artikel |
| Sprache: | en |
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American Society for Microbiology
2001
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC114581/ https://ncbi.nlm.nih.gov/pubmed/11581375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.21.10065-10072.2001 |
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