Inherent Instability of Poliovirus Genomes Containing Two Internal Ribosome Entry Site (IRES) Elements Supports a Role for the IRES in Encapsidation

Previous studies have described poliovirus genomes in which the internal ribosome entry (IRES) for encephalomyocarditis virus (EMCV) is positioned between the P1 and P2-P3 open reading frames of the poliovirus genome. Although these dicistronic poliovirus genomes were replication competent, most exh...

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Bibliografiske detaljer
Main Authors: Johansen, Lisa K., Morrow, Casey D.
Format: Artigo
Sprog:en
Udgivet: American Society for Microbiology 2000
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC116343/
https://ncbi.nlm.nih.gov/pubmed/10954532
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC116343/
https://ncbi.nlm.nih.gov/pubmed/10954532

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