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Regulation of the Raf-1 kinase domain by phosphorylation and 14-3-3 association.

The Raf-1 kinase domain is kept in an inactive state by the N-terminal regulatory domain. Activation of the kinase domain occurs following release from the N-terminal repression and possible catalytic upregulation. To distinguish the regulatory mechanisms that directly influence the catalytic activi...

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Bibliografske podrobnosti
Main Authors: Yip-Schneider, M T, Miao, W, Lin, A, Barnard, D S, Tzivion, G, Marshall, M S
Format: Artigo
Jezik:English
Izdano: 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221345/
https://ncbi.nlm.nih.gov/pubmed/10998357
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