Alkoxyalkyl Esters of Cidofovir and Cyclic Cidofovir Exhibit Multiple-Log Enhancement of Antiviral Activity against Cytomegalovirus and Herpesvirus Replication In Vitro

The incidence of cytomegalovirus (CMV) retinitis is declining in AIDS patients but remains a significant clinical problem in patients with organ transplants and bone marrow transplants. Prophylaxis with ganciclovir (GCV) or valganciclovir reduces the incidence of CMV disease but may lead to the emer...

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Main Authors: Beadle, James R., Hartline, Caroll, Aldern, Kathy A., Rodriguez, Natalie, Harden, Emma, Kern, Earl R., Hostetler, Karl Y.
Formato: Artigo
Idioma:en
Publicado: American Society for Microbiology 2002
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC127379/
https://ncbi.nlm.nih.gov/pubmed/12121908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2381-2386.2002
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https://ncbi.nlm.nih.gov/pmc/articles/PMC127379/
https://ncbi.nlm.nih.gov/pubmed/12121908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2381-2386.2002

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