TY  - JOUR
T1  - Linkage Disequilibrium Mapping of Quantitative-Trait Loci by Selective Genotyping
A1  - Chen, Zehua
LA  - English
PB  - The American Society of Human Genetics
YR  - 2005
UL  - http://buscaintegrada.pucsp.br/vufind/Record/pubmed-1275615
AB  - The principles of linkage disequilibrium mapping of dichotomous diseases can be well applied to the mapping of quantitative-trait loci through the method of selective genotyping. In 1999, M. Slatkin considered a truncation selection (TS) approach. We propose in this report an extended TS approach and an extreme-rank-selection (ERS) approach. The properties of these selection approaches are studied analytically. By using a simulation study, we demonstrate that both the extended TS approach and the ERS approach provide remarkable improvements over Slatkin’s original TS approach.
KW  - Report
ER  -