Human Monocytes Kill Shigella flexneri but Then Die by Apoptosis Associated with Suppression of Proinflammatory Cytokine Production

Shigella flexneri infection of human macrophages is followed by rapid bacterial escape into the cytosol and secretion of IpaB, which activates caspase-1 to mediate cell death and release of mature interleukin (IL)-1β. Here we report a different outcome following infection of human peripheral blood m...

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Hlavní autoři: Hathaway, Lucy J., Griffin, George E., Sansonetti, Philippe J., Edgeworth, Jonathan D.
Médium: Článek
Jazyk:en
Vydáno: American Society for Microbiology 2002
Témata:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC128053/
https://ncbi.nlm.nih.gov/pubmed/12065527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3833-3842.2002
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https://ncbi.nlm.nih.gov/pmc/articles/PMC128053/
https://ncbi.nlm.nih.gov/pubmed/12065527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3833-3842.2002

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