Coadministration of an Interleukin-12 Gene and a Trypanosoma cruzi Gene Improves Vaccine Efficacy

We tested the immunogenicity of two Trypanosoma cruzi antigens injected into mice in the form of DNA vaccine. Immunization with DNA encoding dihydroorotate dehydrogenase did not confer protective immunity in all mouse strains tested. Immunization with DNA encoding trans-sialidase surface antigen (TS...

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Autors principals: Katae, Masaharu, Miyahira, Yasushi, Takeda, Kazuyoshi, Matsuda, Hironori, Yagita, Hideo, Okumura, Ko, Takeuchi, Tsutomu, Kamiyama, Tsuneo, Ohwada, Akihiko, Fukuchi, Yoshinosuke, Aoki, Takashi
Format: Article
Idioma:en
Publicat: American Society for Microbiology 2002
Matèries:
Fungal and Parasitic Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC128276/
https://ncbi.nlm.nih.gov/pubmed/12183527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.4833-4840.2002
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