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Direct inhibition of microtubule-based kinesin motility by local anesthetics.
Local anesthetics are known to inhibit neuronal fast anterograde axoplasmic transport (FAAT) in a reversible and dose-dependent manner, but the precise mechanism has not been determined. FAAT is powered by kinesin superfamily proteins, which transport membranous organelles, vesicles, or protein comp...
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| Autors principals: | , , , , , |
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| Format: | Article |
| Idioma: | English |
| Publicat: |
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1300696/ https://ncbi.nlm.nih.gov/pubmed/10653806 |
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