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Probing Conformational Changes of Gramicidin Ion Channels by Single-Molecule Patch-Clamp Fluorescence Microscopy

Complex conformational changes influence and regulate the dynamics of ion channels. Such conformational changes are stochastic and often inhomogeneous, which makes it extremely difficult, if not impossible, to characterize them by ensemble-averaged experiments or by single-channel recordings of the...

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Autors principals: Harms, Greg S., Orr, Galya, Montal, Mauricio, Thrall, Brian D., Colson, Steve D., Lu, H. Peter
Format: Article
Idioma:English
Publicat: Biophysical Society 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303355/
https://ncbi.nlm.nih.gov/pubmed/12944296
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