Variables Affecting In Vivo Performance of High-Capacity Adenovirus Vectors

In high-capacity adenovirus (HC-Ad) vectors the size and/or composition of the vector genome influences vector stability during production and the expression profile following gene transfer. Typically, an HC-Ad vector will contain both a gene or an expression cassette and stuffer DNA that is require...

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Hauptverfasser: Schiedner, Gudrun, Hertel, Sabine, Johnston, Marion, Biermann, Volker, Dries, Volker, Kochanek, Stefan
Format: Artikel
Sprache:en
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Gene Therapy
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC135880/
https://ncbi.nlm.nih.gov/pubmed/11799154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.4.1600-1609.2002
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https://ncbi.nlm.nih.gov/pmc/articles/PMC135880/
https://ncbi.nlm.nih.gov/pubmed/11799154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.4.1600-1609.2002

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