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Homology Modeling Identifies C-Terminal Residues that Contribute to the Ca(2+) Sensitivity of a BK(Ca) Channel

Activation of BK(Ca) channels by direct Ca(2+) binding and membrane depolarization occur via independent and additive molecular processes. The “calcium bowl” domain is critically involved in Ca(2+)-dependent gating, and we have hypothesized that a sequence within this domain may resemble an EF hand...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Sheng, Jian-Zhong, Weljie, Aalim, Sy, Lusia, Ling, Shizhang, Vogel, Hans J., Braun, Andrew P.
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Biophysical Society 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366805/
https://ncbi.nlm.nih.gov/pubmed/16100257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.063610
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