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Ku is required for telomeric C-rich strand maintenance but not for end-to-end chromosome fusions in Arabidopsis
Telomere dysfunction arising from mutations in telomerase or in telomere capping proteins leads to end-to-end chromosome fusions. Paradoxically, the Ku70/80 heterodimer, essential for nonhomologous end-joining double-strand break repair, is also found at telomeres, and in mammals it is required to p...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | en |
| Udgivet: |
The National Academy of Sciences
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC141044/ https://ncbi.nlm.nih.gov/pubmed/12511598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0236128100 |
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