Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype

Midbrain dopamine (DA) neurons play a central role in the regulation of voluntary movement, and their degeneration is associated with Parkinson’s disease. Cell replacement therapies, and in particular embryonic stem (ES) cell-derived DA neurons, offer a potential therapeutic venue for Parkinson’s di...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Martinat, Cecile, Bacci, Jean-Jacques, Leete, Thomas, Kim, Jongpil, Vanti, William B., Newman, Amy H., Cha, Joo H., Gether, Ulrik, Wang, Honggang, Abeliovich, Asa
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: National Academy of Sciences 2006
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413837/
https://ncbi.nlm.nih.gov/pubmed/16477036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511153103
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