Differential regulation of NF-κB activation and function by topoisomerase II inhibitors

BACKGROUND: While many common chemotherapeutic drugs and other inducers of DNA-damage result in both NF-κB nuclear translocation and DNA-binding, we have previously observed that, depending on the precise stimulus, there is great diversity of the function of NF-κB. In particular, we found that treat...

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Main Authors: Campbell, Kirsteen J, O'Shea, John M, Perkins, Neil D
Formato: Artigo
Idioma:English
Publicado: BioMed Central 2006
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459870/
https://ncbi.nlm.nih.gov/pubmed/16630341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-101
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1459870/
https://ncbi.nlm.nih.gov/pubmed/16630341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-101

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