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Detecting bottlenecks and selective sweeps from DNA sequence polymorphism.
A coalescence-based maximum-likelihood method is presented that aims to (i) detect diversity-reducing events in the recent history of a population and (ii) distinguish between demographic (e.g., bottlenecks) and selective causes (selective sweep) of a recent reduction of genetic variability. The for...
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| Hauptverfasser: | , , |
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| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
2000
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1461106/ https://ncbi.nlm.nih.gov/pubmed/10835415 |
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