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Conformational Heterogeneity in RNA Polymerase Observed by Single-Pair FRET Microscopy
Kinetic, structural, and single-molecule transcription measurements suggest that RNA polymerase can adopt many different conformations during elongation. We have measured the geometry of the DNA and RNA in ternary elongation complexes using single-pair fluorescence resonance energy transfer. Six dif...
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| Autori principali: | , , , , |
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| Natura: | Articolo |
| Lingua: | English |
| Pubblicazione: |
Biophysical Society
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1471840/ https://ncbi.nlm.nih.gov/pubmed/16581837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.078840 |
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