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Chromatin remodeling of the interleukin-2 gene: distinct alterations in the proximal versus distal enhancer regions.

Known transcription factor-DNA interactions in the minimal enhancer of the murine interleukin-2 gene (IL-2) do not easily explain the T cell specificity of IL-2 regulation. To seek additional determinants of cell type specificity, in vivo methodologies were employed to examine chromatin structure 5&...

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Main Authors: Ward, S B, Hernandez-Hoyos, G, Chen, F, Waterman, M, Reeves, R, Rothenberg, E V
格式: Artigo
語言:en
出版: 1998
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC147656/
https://ncbi.nlm.nih.gov/pubmed/9611237
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