TAR-RNA binding by HIV-1 Tat protein is selectively inhibited by its L-enantiomer.

An oligoribonucleotide, corresponding to the Tat-interactive top half of the HIV-1 TAR RNA stem-loop, was synthesized in both the natural D- and the enantiomeric L-configurations. The affinity of Tat for the two RNAs, assessed by competition binding experiments, was found to be identical and is redu...

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Detaylı Bibliyografya
Asıl Yazarlar: Garbesi, A, Hamy, F, Maffini, M, Albrecht, G, Klimkait, T
Materyal Türü: Makale
Dil:en
Baskı/Yayın Bilgisi: 1998
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC147661/
https://ncbi.nlm.nih.gov/pubmed/9611232
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC147661/
https://ncbi.nlm.nih.gov/pubmed/9611232

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