Helicobacter pylori Initiates the Stringent Response upon Nutrient and pH Downshift

Helicobacter pylori was previously reported to lack a stringent response. In contrast, we show that after nutrient downshift, H. pylori produced abundant ppGpp and less total RNA. pH downshift also caused (p)ppGpp accumulation. Our observations indicate that nutrient deprivation and acid shock activ...

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Principais autores: Wells, Derek H., Gaynor, Erin C.
Formato: Artigo
Idioma:English
Publicado em: American Society for Microbiology 2006
Assuntos:
Physiology and Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482847/
https://ncbi.nlm.nih.gov/pubmed/16672627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.188.10.3726-3729.2006
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spelling pubmed-14828472006-09-01 Helicobacter pylori Initiates the Stringent Response upon Nutrient and pH Downshift Wells, Derek H. Gaynor, Erin C. J Bacteriol Physiology and Metabolism Helicobacter pylori was previously reported to lack a stringent response. In contrast, we show that after nutrient downshift, H. pylori produced abundant ppGpp and less total RNA. pH downshift also caused (p)ppGpp accumulation. Our observations indicate that nutrient deprivation and acid shock activate the stringent response in H. pylori. American Society for Microbiology 2006-05 /pmc/articles/PMC1482847/ /pubmed/16672627 http://dx.doi.org/10.1128/JB.188.10.3726-3729.2006 Text en Copyright © 2006, American Society for Microbiology
institution US National Library of Medicine
collection PubMed Central
language English
format Article
topic Physiology and Metabolism
spellingShingle Physiology and Metabolism
Wells, Derek H.
Gaynor, Erin C.
Helicobacter pylori Initiates the Stringent Response upon Nutrient and pH Downshift
description Helicobacter pylori was previously reported to lack a stringent response. In contrast, we show that after nutrient downshift, H. pylori produced abundant ppGpp and less total RNA. pH downshift also caused (p)ppGpp accumulation. Our observations indicate that nutrient deprivation and acid shock activate the stringent response in H. pylori.
author Wells, Derek H.
Gaynor, Erin C.
author_facet Wells, Derek H.
Gaynor, Erin C.
author_sort Wells, Derek H.
title Helicobacter pylori Initiates the Stringent Response upon Nutrient and pH Downshift
title_short Helicobacter pylori Initiates the Stringent Response upon Nutrient and pH Downshift
title_full Helicobacter pylori Initiates the Stringent Response upon Nutrient and pH Downshift
title_fullStr Helicobacter pylori Initiates the Stringent Response upon Nutrient and pH Downshift
title_full_unstemmed Helicobacter pylori Initiates the Stringent Response upon Nutrient and pH Downshift
title_sort helicobacter pylori initiates the stringent response upon nutrient and ph downshift
publisher American Society for Microbiology
publisher_facet American Society for Microbiology
publishDate 2006
url https://ncbi.nlm.nih.gov/pmc/articles/PMC1482847/
https://ncbi.nlm.nih.gov/pubmed/16672627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.188.10.3726-3729.2006
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