The Interaction of Acridine Dyes with the Densely Packed DNA of Bacteriophage

The interactions of acridine dyes with intact phage DNA differ from those with extracted DNA in the following respects. Strong binding (intercalation) is greatly reduced in intact phage but probably not eliminated. The cooperative, weak binding is stronger and the stacking tendency is increased. In...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dusenbery, David B., Uretz, Robert B.
Formato: Artigo
Idioma:English
Publicado em: 1972
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1484235/
https://ncbi.nlm.nih.gov/pubmed/5044579
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
id pubmed-1484235
record_format dspace
spelling pubmed-14842352006-07-04 The Interaction of Acridine Dyes with the Densely Packed DNA of Bacteriophage Dusenbery, David B. Uretz, Robert B. Biophys J Articles The interactions of acridine dyes with intact phage DNA differ from those with extracted DNA in the following respects. Strong binding (intercalation) is greatly reduced in intact phage but probably not eliminated. The cooperative, weak binding is stronger and the stacking tendency is increased. In gels of DNA the stacking tendency is seen to increase with decreasing hydration. These influences of the dense packing of DNA must be taken into account when using basic dyes to study chromosome structure. 1972-08 /pmc/articles/PMC1484235/ /pubmed/5044579 Text en
institution US National Library of Medicine
collection PubMed Central
language English
format Article
topic Articles
spellingShingle Articles
Dusenbery, David B.
Uretz, Robert B.
The Interaction of Acridine Dyes with the Densely Packed DNA of Bacteriophage
description The interactions of acridine dyes with intact phage DNA differ from those with extracted DNA in the following respects. Strong binding (intercalation) is greatly reduced in intact phage but probably not eliminated. The cooperative, weak binding is stronger and the stacking tendency is increased. In gels of DNA the stacking tendency is seen to increase with decreasing hydration. These influences of the dense packing of DNA must be taken into account when using basic dyes to study chromosome structure.
author Dusenbery, David B.
Uretz, Robert B.
author_facet Dusenbery, David B.
Uretz, Robert B.
author_sort Dusenbery, David B.
title The Interaction of Acridine Dyes with the Densely Packed DNA of Bacteriophage
title_short The Interaction of Acridine Dyes with the Densely Packed DNA of Bacteriophage
title_full The Interaction of Acridine Dyes with the Densely Packed DNA of Bacteriophage
title_fullStr The Interaction of Acridine Dyes with the Densely Packed DNA of Bacteriophage
title_full_unstemmed The Interaction of Acridine Dyes with the Densely Packed DNA of Bacteriophage
title_sort interaction of acridine dyes with the densely packed dna of bacteriophage
publishDate 1972
url https://ncbi.nlm.nih.gov/pmc/articles/PMC1484235/
https://ncbi.nlm.nih.gov/pubmed/5044579
_version_ 1760314565292195840

Registos relacionados