Oxidized ATP Protection against Anthrax Lethal Toxin

Bacillus anthracis lethal toxin (LT) induces rapid lysis (<90 min) of murine macrophages from certain inbred strains. The mechanism for LT-induced cytolysis is currently unknown. We hypothesized that the ATP-activated macrophage P2X7 receptors implicated in nucleotide-mediated macrophage lysis co...

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Bibliographic Details
Main Authors: Moayeri, Mahtab, Wickliffe, Katherine E., Wiggins, Jason F., Leppla, Stephen H.
Format: Article
Language:English
Published: American Society for Microbiology 2006
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489720/
https://ncbi.nlm.nih.gov/pubmed/16790743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00051-06
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1489720/
https://ncbi.nlm.nih.gov/pubmed/16790743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00051-06

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