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Adipose-derived resistin and gut-derived resistin-like molecule–β selectively impair insulin action on glucose production
The adipose-derived hormone resistin is postulated to link obesity to insulin resistance and diabetes. Here, the infusion of either resistin or the resistin-like molecule–β (RELMβ) rapidly induced severe hepatic but not peripheral insulin resistance. In the presence of physiologic hyperinsulinemia,...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | en |
| Udgivet: |
American Society for Clinical Investigation
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151868/ https://ncbi.nlm.nih.gov/pubmed/12531878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316521 |
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