Synergistic Protection of Mice against Plague with Monoclonal Antibodies Specific for the F1 and V Antigens of Yersinia pestis

Monoclonal antibodies specific for Yersinia pestis V antigen and F1 antigen, administered singly or in combination, protected mice in models of bubonic and pneumonic plague. Antibodies showed synergy when administered prophylactically and as a therapy 48 h postinfection. Monoclonal antibodies theref...

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Autors principals: Hill, Jim, Copse, Catherine, Leary, Sophie, Stagg, Anthony J., Williamson, E. Diane, Titball, Richard W.
Format: Article
Idioma:en
Publicat: American Society for Microbiology 2003
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC152045/
https://ncbi.nlm.nih.gov/pubmed/12654847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.2234-2238.2003
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https://ncbi.nlm.nih.gov/pmc/articles/PMC152045/
https://ncbi.nlm.nih.gov/pubmed/12654847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.2234-2238.2003

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