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The generation of memory cells. IV. Immunization with antigen-antibody complexes accelerates the development of B-memory cells, the formation of germinal centres and the maturation of antibody affinity in the secondary response.
Hapten (DNP)-specific B-memory cells were induced by priming mice with soluble or alum precipitated DNP-haemocyanin (KLH) plus Bordetella pertussis or CNP-KLH-anti-DNP antibody complexes at equivalence. Cells from mice given complexes gave a substantial adoptive IgG response five days after priming,...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
1981
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1555022/ https://ncbi.nlm.nih.gov/pubmed/7019054 |
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