Transposon-Assisted Cloning and Traceless Mutagenesis of Adenoviruses: Development of a Novel Vector Based on Species D

Until recently, adenovirus (Ad)-mediated gene therapy was almost exclusively based on human Ad type 5 (Ad5). Preexisting immunity and the limited, coxsackievirus and adenovirus receptor-dependent tropism of Ad5 stimulated attempts to exploit the natural diversity in tropism of the other 50 known hum...

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Bibliografiske detaljer
Main Authors: Ruzsics, Zsolt, Wagner, Markus, Osterlehner, Andrea, Cook, Jonathan, Koszinowski, Ulrich, Burgert, Hans-Gerhard
Format: Artigo
Sprog:English
Udgivet: American Society for Microbiology 2006
Fag:
Gene Delivery
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563829/
https://ncbi.nlm.nih.gov/pubmed/16873266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00687-06
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC1563829/
https://ncbi.nlm.nih.gov/pubmed/16873266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00687-06

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