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Effects of a quaternary bupivacaine derivative on delayed rectifier K(+) currents

1. Block of hKv1.5 channels by R-bupivacaine has been attributed to the interaction of the charged form of the drug with an intracellular receptor. However, bupivacaine is present as a mixture of neutral and charged forms both extra- and intracellularly. 2. We have studied the effects produced by th...

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Bibliografski detalji
Glavni autori: Longobardo, M, González, T, Navarro-Polanco, R, Caballero, R, Delpón, E, Tamargo, J, Snyders, D J, Tamkun, M M, Valenzuela, C
Format: Članak
Jezik:English
Izdano: 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572085/
https://ncbi.nlm.nih.gov/pubmed/10807678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703334
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