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Activation of NF-κB by the intracellular expression of NF-κB-inducing kinase acts as a powerful vaccine adjuvant

There is a pressing need for adjuvants that will enhance the effectiveness of genetic vaccines. This is particularly important in cancer and infectious disease such as HIV and malaria for which successful vaccines are desperately needed. Here, we describe an approach to enhance immunogenicity that i...

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Библиографические подробности
Главные авторы: Andreakos, E., Williams, R. O., Wales, J., Foxwell, B. M., Feldmann, M.
Формат: Статья
Язык:English
Опубликовано: National Academy of Sciences 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599984/
https://ncbi.nlm.nih.gov/pubmed/16971487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603493103
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