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Increased Production of Folate by Metabolic Engineering of Lactococcus lactis

The dairy starter bacterium Lactococcus lactis is able to synthesize folate and accumulates large amounts of folate, predominantly in the polyglutamyl form. Only small amounts of the produced folate are released in the extracellular medium. Five genes involved in folate biosynthesis were identified...

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Bibliografische gegevens
Hoofdauteurs: Sybesma, Wilbert, Starrenburg, Marjo, Kleerebezem, Michiel, Mierau, Igor, de Vos, Willem M., Hugenholtz, Jeroen
Formaat: Artikel
Taal:en
Gepubliceerd in: American Society for Microbiology 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC161528/
https://ncbi.nlm.nih.gov/pubmed/12788700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.6.3069-3076.2003
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