Alternate Polypurine Tracts Affect Rous Sarcoma Virus Integration In Vivo

When the endogenous polypurine tract (PPT) of the Rous sarcoma virus (RSV)-derived vector RSVP(A)Z was replaced with alternate retroviral PPTs, the fraction of unintegrated viral DNA with the normal consensus ends significantly decreased and the retention of part of the PPT significantly increased....

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Autores principales: Oh, Jangsuk, Chang, Kevin W., Alvord, W. Gregory, Hughes, Stephen H.
Formato: Artículo
Lenguaje:English
Publicado: American Society for Microbiology 2006
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617299/
https://ncbi.nlm.nih.gov/pubmed/17005708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00361-06
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1617299/
https://ncbi.nlm.nih.gov/pubmed/17005708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00361-06

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