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Pregnenolone binds to microtubule-associated protein 2 and stimulates microtubule assembly
Fetal or adult rat-brain cytosol and fetal rat-brain microtubules contain a high-affinity, low-capacity pregnenolone-binding protein. The equilibrium dissociation constant is in the 30–50 nM range. The best competitors (in decreasing order) are pregnenolone sulfate, progesterone, Δ5-pregnene-3β,20α-...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | en |
| Publicado: |
The National Academy of Sciences
2000
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC16282/ https://ncbi.nlm.nih.gov/pubmed/10737804 |
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