Oral contraceptive use and venous thromboembolism: absence of an effect of smoking.

We conducted a case-control study to test the hypothesis that women smokers who use oral contraceptives have an increased risk of developing venous thrombosis. Patients and controls were drawn from two sets of hospital patients already included in the Boston Collaborative Drug Surveillance Programme...

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Main Authors: Lawson, D H, Davidson, J F, Jick, H
格式: Artigo
語言:English
出版: 1977
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1632037/
https://ncbi.nlm.nih.gov/pubmed/334332
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spelling pubmed-16320372006-11-02 Oral contraceptive use and venous thromboembolism: absence of an effect of smoking. Lawson, D H Davidson, J F Jick, H Br Med J Research Article We conducted a case-control study to test the hypothesis that women smokers who use oral contraceptives have an increased risk of developing venous thrombosis. Patients and controls were drawn from two sets of hospital patients already included in the Boston Collaborative Drug Surveillance Programme. Sixty patients with uncomplicated thromboembolism were matched with 180 controls with other diagnoses; all were premenopausal women taking oral contraceptives. Patients with conditions that might predispose to thromboembolism or be related to smoking were excluded. We found no association between smoking habits and thromboembolism. Similarly, we found no association between thromboembolism, smoking, and duration of oral contraceptive use. Thus we conclude that differences in fibrinolytic activity between smokers and non-smokers are not major factors in the aetiology of uncomplicated thromboembolism in women using oral contraceptives. 1977-09-17 /pmc/articles/PMC1632037/ /pubmed/334332 Text en
institution US National Library of Medicine
collection PubMed Central
language English
format Article
topic Research Article
spellingShingle Research Article
Lawson, D H
Davidson, J F
Jick, H
Oral contraceptive use and venous thromboembolism: absence of an effect of smoking.
description We conducted a case-control study to test the hypothesis that women smokers who use oral contraceptives have an increased risk of developing venous thrombosis. Patients and controls were drawn from two sets of hospital patients already included in the Boston Collaborative Drug Surveillance Programme. Sixty patients with uncomplicated thromboembolism were matched with 180 controls with other diagnoses; all were premenopausal women taking oral contraceptives. Patients with conditions that might predispose to thromboembolism or be related to smoking were excluded. We found no association between smoking habits and thromboembolism. Similarly, we found no association between thromboembolism, smoking, and duration of oral contraceptive use. Thus we conclude that differences in fibrinolytic activity between smokers and non-smokers are not major factors in the aetiology of uncomplicated thromboembolism in women using oral contraceptives.
author Lawson, D H
Davidson, J F
Jick, H
author_facet Lawson, D H
Davidson, J F
Jick, H
author_sort Lawson, D H
title Oral contraceptive use and venous thromboembolism: absence of an effect of smoking.
title_short Oral contraceptive use and venous thromboembolism: absence of an effect of smoking.
title_full Oral contraceptive use and venous thromboembolism: absence of an effect of smoking.
title_fullStr Oral contraceptive use and venous thromboembolism: absence of an effect of smoking.
title_full_unstemmed Oral contraceptive use and venous thromboembolism: absence of an effect of smoking.
title_sort oral contraceptive use and venous thromboembolism: absence of an effect of smoking.
publishDate 1977
url https://ncbi.nlm.nih.gov/pmc/articles/PMC1632037/
https://ncbi.nlm.nih.gov/pubmed/334332
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