Carregant...
Mycobacterium tuberculosis Malate Synthase- and MPT51-Based Serodiagnostic Assay as an Adjunct to Rapid Identification of Pulmonary Tuberculosis
The 81-kDa malate synthase (MS; Rv 1837c) and the 27-kDa MPT51 (Rv 3803c) of Mycobacterium tuberculosis are immunodominant antigens recognized by serum antibodies from ∼80% of human immunodeficiency virus-negative smear-positive tuberculosis patients from India. We now provide evidence that the use...
Guardat en:
| Autors principals: | , , , , , , , , |
|---|---|
| Format: | Article |
| Idioma: | English |
| Publicat: |
American Society for Microbiology
2006
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1656542/ https://ncbi.nlm.nih.gov/pubmed/17090645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00158-06 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|
| id |
pubmed-1656542 |
|---|---|
| record_format |
dspace |
| spelling |
pubmed-16565422007-03-01 Mycobacterium tuberculosis Malate Synthase- and MPT51-Based Serodiagnostic Assay as an Adjunct to Rapid Identification of Pulmonary Tuberculosis Achkar, Jacqueline M. Dong, Yuxin Holzman, Robert S. Belisle, John Kourbeti, Irene S. Sherpa, Tsering Condos, Rany Rom, William N. Laal, Suman Clin Vaccine Immunol Clinical and Diagnostic Laboratory Immunology The 81-kDa malate synthase (MS; Rv 1837c) and the 27-kDa MPT51 (Rv 3803c) of Mycobacterium tuberculosis are immunodominant antigens recognized by serum antibodies from ∼80% of human immunodeficiency virus-negative smear-positive tuberculosis patients from India. We now provide evidence that the use of the MS/MPT51-based serodiagnostic assay can serve as an adjunct to sputum microscopy in the rapid diagnosis of pulmonary tuberculosis. American Society for Microbiology 2006-11 /pmc/articles/PMC1656542/ /pubmed/17090645 http://dx.doi.org/10.1128/CVI.00158-06 Text en Copyright © 2006, American Society for Microbiology |
| institution |
US National Library of Medicine |
| collection |
PubMed Central |
| language |
English |
| format |
Article |
| topic |
Clinical and Diagnostic Laboratory Immunology |
| spellingShingle |
Clinical and Diagnostic Laboratory Immunology Achkar, Jacqueline M. Dong, Yuxin Holzman, Robert S. Belisle, John Kourbeti, Irene S. Sherpa, Tsering Condos, Rany Rom, William N. Laal, Suman Mycobacterium tuberculosis Malate Synthase- and MPT51-Based Serodiagnostic Assay as an Adjunct to Rapid Identification of Pulmonary Tuberculosis |
| description |
The 81-kDa malate synthase (MS; Rv 1837c) and the 27-kDa MPT51 (Rv 3803c) of Mycobacterium tuberculosis are immunodominant antigens recognized by serum antibodies from ∼80% of human immunodeficiency virus-negative smear-positive tuberculosis patients from India. We now provide evidence that the use of the MS/MPT51-based serodiagnostic assay can serve as an adjunct to sputum microscopy in the rapid diagnosis of pulmonary tuberculosis. |
| author |
Achkar, Jacqueline M. Dong, Yuxin Holzman, Robert S. Belisle, John Kourbeti, Irene S. Sherpa, Tsering Condos, Rany Rom, William N. Laal, Suman |
| author_facet |
Achkar, Jacqueline M. Dong, Yuxin Holzman, Robert S. Belisle, John Kourbeti, Irene S. Sherpa, Tsering Condos, Rany Rom, William N. Laal, Suman |
| author_sort |
Achkar, Jacqueline M. |
| title |
Mycobacterium tuberculosis Malate Synthase- and MPT51-Based Serodiagnostic Assay as an Adjunct to Rapid Identification of Pulmonary Tuberculosis |
| title_short |
Mycobacterium tuberculosis Malate Synthase- and MPT51-Based Serodiagnostic Assay as an Adjunct to Rapid Identification of Pulmonary Tuberculosis |
| title_full |
Mycobacterium tuberculosis Malate Synthase- and MPT51-Based Serodiagnostic Assay as an Adjunct to Rapid Identification of Pulmonary Tuberculosis |
| title_fullStr |
Mycobacterium tuberculosis Malate Synthase- and MPT51-Based Serodiagnostic Assay as an Adjunct to Rapid Identification of Pulmonary Tuberculosis |
| title_full_unstemmed |
Mycobacterium tuberculosis Malate Synthase- and MPT51-Based Serodiagnostic Assay as an Adjunct to Rapid Identification of Pulmonary Tuberculosis |
| title_sort |
mycobacterium tuberculosis malate synthase- and mpt51-based serodiagnostic assay as an adjunct to rapid identification of pulmonary tuberculosis |
| publisher |
American Society for Microbiology |
| publisher_facet |
American Society for Microbiology |
| publishDate |
2006 |
| url |
https://ncbi.nlm.nih.gov/pmc/articles/PMC1656542/ https://ncbi.nlm.nih.gov/pubmed/17090645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00158-06 |
| _version_ |
1760337462692937728 |