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Innate immunity against vaccinia virus is mediated by TLR2 and requires TLR-independent production of IFN-β
Vaccinia virus (VV) has been used extensively as a vaccine vehicle in the clinical application for infectious diseases and cancer. Previous studies have suggested that the unique potency of VV-based vaccine lies in its effective activation of the innate immune system. However, how VV activates innat...
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| Hauptverfasser: | , , , |
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| Format: | Artikel |
| Sprache: | English |
| Veröffentlicht: |
American Society of Hematology
2007
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1785085/ https://ncbi.nlm.nih.gov/pubmed/16973959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-027136 |
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