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A dominant linear B-cell epitope of ricin A-chain is the target of a neutralizing antibody response in Hodgkin's lymphoma patients treated with an anti-CD25 immunotoxin

Hodgkin's lymphoma patients treated with an anti-CD25 Ricin toxin A-chain (RTA)-based Immunotoxin (RFT5.dgA) develop an immune response against the toxic moiety of the immunoconjugate. The anti-RTA antibody response of 15 patients showing different clinical features and receiving different tota...

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Bibliographic Details
Main Authors: CASTELLETTI, D, FRACASSO, G, RIGHETTI, S, TRIDENTE, G, SCHNELL, R, ENGERT, A, COLOMBATTI, M
Format: Article
Language:English
Published: Blackwell Science Inc 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809030/
https://ncbi.nlm.nih.gov/pubmed/15086403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02442.x
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