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AMPK and cell proliferation – AMPK as a therapeutic target for atherosclerosis and cancer

AMPK is a serine/threonine protein kinase, which serves as an energy sensor in all eukaryotic cell types. Published studies indicate that AMPK activation strongly suppresses cell proliferation in non-malignant cells as well as in tumour cells. These actions of AMPK appear to be mediated through mult...

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Autori principali: Motoshima, Hiroyuki, Goldstein, Barry J, Igata, Motoyuki, Araki, Eiichi
Natura: Articolo
Lingua:English
Pubblicazione: Blackwell Science Inc 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817805/
https://ncbi.nlm.nih.gov/pubmed/16613876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.108324
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