Orthotopic Microinjection of Human Colon Cancer Cells in Nude Mice Induces Tumor Foci in All Clinically Relevant Metastatic Sites

Despite metastasis as an important cause of death in colorectal cancer patients, current animal models of this disease are scarcely metastatic. We evaluated whether direct orthotopic cell microinjection, between the mucosa and the muscularis layers of the cecal wall of nude mice, drives tumor foci t...

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Bibliografiske detaljer
Main Authors: Céspedes, María Virtudes, Espina, Carolina, García-Cabezas, Miguel Angel, Trias, Manuel, Boluda, Alicia, Gómez del Pulgar, María Teresa, Sancho, Francesc Josep, Nistal, Manuel, Lacal, Juan Carlos, Mangues, Ramon
Format: Artigo
Sprog:English
Udgivet: American Society for Investigative Pathology 2007
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864873/
https://ncbi.nlm.nih.gov/pubmed/17322390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060773
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC1864873/
https://ncbi.nlm.nih.gov/pubmed/17322390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060773

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