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Frequent Intrapatient Recombination between Human Immunodeficiency Virus Type 1 R5 and X4 Envelopes: Implications for Coreceptor Switch

Emergence of human immunodeficiency virus type 1 (HIV-1) populations that switch or broaden coreceptor usage from CCR5 to CXCR4 is intimately coupled to CD4(+) cell depletion and disease progression toward AIDS. To better understand the molecular mechanisms involved in the coreceptor switch, we dete...

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Détails bibliographiques
Auteurs principaux: Mild, Mattias, Esbjörnsson, Joakim, Fenyö, Eva Maria, Medstrand, Patrik
Format: Article
Langue:English
Publié: American Society for Microbiology 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866041/
https://ncbi.nlm.nih.gov/pubmed/17251288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01295-06
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