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hMLH1 Promoter Hypermethylation Is an Early Event in Human Endometrial Tumorigenesis

It has recently been suggested that silencing of the hMLH1 gene by promoter hypermethylation is the mechanism underlying the presence of the microsatellite instability (MSI) phenotype in sporadic colon and endometrial carcinomas. To determine whether hMLH1 promoter hypermethylation is a relatively e...

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書誌詳細
主要な著者: Esteller, Manel, Catasus, Lluis, Matias-Guiu, Xavier, Mutter, George L., Prat, Jaime, Baylin, Steve B., Herman, James G.
フォーマット: 論文
言語:English
出版事項: American Society for Investigative Pathology 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866976/
https://ncbi.nlm.nih.gov/pubmed/10550333
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