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Zebrafish G protein γ(2) is required for VEGF signaling during angiogenesis

Vascular endothelial growth factor (VEGF) is a major mediator of pathologic angiogenesis, a process necessary for the formation of new blood vessels to support tumor growth. Historically, VEGF has been thought to signal via receptor tyrosine kinases, which are not typically considered to be G protei...

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Главные авторы: Leung, TinChung, Chen, Hui, Stauffer, Anna M., Giger, Kathryn E., Sinha, Soniya, Horstick, Eric J., Humbert, Jasper E., Hansen, Carl A., Robishaw, Janet D.
Формат: Статья
Язык:English
Опубликовано: The American Society of Hematology 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895829/
https://ncbi.nlm.nih.gov/pubmed/16537812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-09-3706
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