Physiologic self antigens rapidly capacitate autoimmune disease-specific polyclonal CD4(+)CD25(+) regulatory T cells

Studies on CD4(+)CD25(+) regulatory T cells (Tregs) with transgenic T-cell receptors indicate that Tregs may receive continuous antigen (Ag) stimulation in the periphery. However, the consequence of this Ag encounter and its relevance to physiologic polyclonal Treg function are not established. In a...

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Hlavní autoři: Setiady, Yulius Y., Ohno, Katsuhiro, Samy, Eileen T., Bagavant, Harini, Qiao, Hui, Sharp, Colin, She, Jin Xiong, Tung, Kenneth S. K.
Médium: Článek
Jazyk:English
Vydáno: © 2006 by The American Society of Hematology 2006
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895904/
https://ncbi.nlm.nih.gov/pubmed/16223778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-08-3088
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1895904/
https://ncbi.nlm.nih.gov/pubmed/16223778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-08-3088

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