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The role of gamma-glutamyl transpeptidase in the nephrotoxicity of an Agaricus bisporus metabolite.
The mushroom metabolite gamma-L-glutaminyl-3,4-dihydroxybenzene (GDHB) was found to have an LD50 of 100 to 200 mg/kg in neonatal C57Bl/6J mice. Adult mice given 200 mg/kg GDHB showed histopathologic evidence of proximal convoluted tubular injury as early as 2 hours after injection, which progressed...
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| Autors principals: | , , , |
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| Format: | Article |
| Idioma: | English |
| Publicat: |
1980
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1903552/ https://ncbi.nlm.nih.gov/pubmed/6106387 |
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