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Rotavirus VP1 alone specifically binds to the 3' end of viral mRNA, but the interaction is not sufficient to initiate minus-strand synthesis.

Recent studies have shown that disrupted (open) rotavirus cores have an associated replicase activity which supports the synthesis of dsRNA from viral mRNA in a cell-free system (D. Chen, C. Q.-Y. Zeng, M. J. Wentz, M. Gorziglia, M. K. Estes, and R. F. Ramig, J. Virol. 68:7030-7039, 1994). To determ...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Patton, J T, Funkhouser, A W, Raychaudhuri, G, Purcell, R H, Govindarajan, S, Elkins, R, Emerson, S U, Rizza, P, Santini, S M, Logozzi, M A, Lapenta, C, Sestili, P, Gherardi, G, Lande, R, Spada, M, Parlato, S, Belardelli, F, Fais, S, Ellison, K S, Peng, W, McFadden, G, Wirblich, C, Thiel, H J, Meyers, G, Tyler, K L, Squier, M K, Brown, A L, Pike, B, Willis, D, Oberhaus, S M, Dermody, T S, Cohen, J J, Shahabuddin, M, Bentsman, G, Volsky, B, Rodriguez, I, Volsky, D J, Schiedner, G, Doerfler, W, Hooker, D J, Tachedjian, G, Solomon, A E, Gurusinghe, A D, Land, S, Birch, C, Anderson, J L, Roy, B M, Arnold, E, Deacon, N J, Moir, S, Perreault, J, Poulin, L, Zheng, Z, Maidji, E, Tugizov, S, Pereira, L, Guan, Y, Shortridge, K F, Krauss, S, Li, P H, Kawaoka, Y, Webster, R G, Serio, T R, Angeloni, A, Kolman, J L, Gradoville, L, Sun, R, Katz, D A, Van Grunsven, W, Middeldorp, J, Miller, G, Orsini, M J, Debouck, C M, Bichko, V V, Taylor, J M, Rohn, J L, Lauring, A S, Linenberger, M L, Overbaugh, J, Beaudet-Miller, M, Zhang, R, Durkin, J, Gibson, W, Kwong, A D, Hong, Z, Zhang, Q K, Boast, S, de los Santos, K, Begemann, M, Goff, S P, Xiao, X, Li, J, Samulski, R J, Ramírez, J C, Fairén, A, Almendral, J M, Huard, J, Feero, W G, Watkins, S C, Hoffman, E P, Rosenblatt, D J, Glorioso, J C, Mattion, N M, Harnish, E C, Crowley, J C, Reilly, P A, Takizawa, T, Ohashi, K, Nakanishi, Y, Kliche, S, Stitz, L, Mangalam, H, Shi, L, Binz, T, Niemann, H, Briese, T, Lipkin, W I, Hwang, J J, Scuric, Z, Anderson, W F, Stiasny, K, Allison, S L, Marchler-Bauer, A, Kunz, C, Heinz, F X, McCarty, T C, Chattopadhyay, S K, Scherer, M T, Fredrickson, T N, Hartley, J W, Morse, H C, Renne, R, Lagunoff, M, Zhong, W, Ganem, D, Suzuki, N, Sugawara, M, Nuss, D L, Matsuura, Y, Hoffman, L M, Hogan, K T, Cashdollar, L W, Posavad, C M, Koelle, D M, Corey, L, Kadaré, G, David, C, Haenni, A L, Kupfermann, H, Dubovi, E J, Martin, L R, Palmenberg, A C, Spearman, P, Ratner, L, Wellington, J E, Allen, G P, Gooley, A A, Love, D N, Packer, N H, Yan, J X, Whalley, J M, Lohman, B L, Razvi, E S, Welsh, R M, Schaefer, B C, Strominger, J L, Speck, S H, Cornelissen, M, Kampinga, G, Zorgdrager, F, Goudsmit, J, Jarousse, N, Martinat, C, Syan, S, Brahic, M, McAllister, A, Cesarman, E, Nador, R G, Bai, F, Bohenzky, R A, Russo, J J, Moore, P S, Chang, Y, Knowles, D M, Jordan, H L, Howard, J, Sellon, R K, Wildt, D E, Tompkins, W A, Kennedy-Stoskopf, S, Girard, M, Yue, L, Barré-Sinoussi, F, van der Ryst, E, Meignier, B, Muchmore, E, Fultz, P N, Cannon, P M, Kim, N, Kingsman, S M, Kingsman, A J, Tristem, M, Kabat, P, Lieberman, L, Linde, S, Karpas, A, Hill, F, Pleskoff, O, Sol, N, Marrakchi, H, Serlin, M, Seman, M, Alizon, M, Yu, S F, Edelmann, K, Strong, R K, Moebes, A, Rethwilm, A, Linial, M L, Fouchier, R A, Simon, J H, Jaffe, A B, Malim, M H, Condra, J H, Holder, D J, Schleif, W A, Blahy, O M, Danovich, R M, Gabryelski, L J, Graham, D J, Laird, D, Quintero, J C, Rhodes, A, Robbins, H L, Roth, E, Shivaprakash, M, Yang, T, Chodakewitz, J A, Deutsch, P J, Leavitt, R Y, Massari, F E, Mellors, J W, Squires, K E, Steigbigel, R T, Teppler, H, Emini, E A, Taddeo, B, Carlini, F, Verani, P, Engelman, A
التنسيق:	مقال
اللغة:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
منشور في:	1996
الموضوعات:	Research Article
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC190866/ https://ncbi.nlm.nih.gov/pubmed/8892917 https://ncbi.nlm.nih.gov/pmc/articles/PMC190867/ https://ncbi.nlm.nih.gov/pubmed/8892918 https://ncbi.nlm.nih.gov/pmc/articles/PMC190868/ https://ncbi.nlm.nih.gov/pubmed/8892919 https://ncbi.nlm.nih.gov/pmc/articles/PMC190869/ https://ncbi.nlm.nih.gov/pubmed/8892920 https://ncbi.nlm.nih.gov/pmc/articles/PMC190870/ https://ncbi.nlm.nih.gov/pubmed/8892921 https://ncbi.nlm.nih.gov/pmc/articles/PMC190871/ https://ncbi.nlm.nih.gov/pubmed/8892922 https://ncbi.nlm.nih.gov/pmc/articles/PMC190872/ https://ncbi.nlm.nih.gov/pubmed/8892923 https://ncbi.nlm.nih.gov/pmc/articles/PMC190873/ https://ncbi.nlm.nih.gov/pubmed/8892924 https://ncbi.nlm.nih.gov/pmc/articles/PMC190874/ https://ncbi.nlm.nih.gov/pubmed/8892925 https://ncbi.nlm.nih.gov/pmc/articles/PMC190875/ https://ncbi.nlm.nih.gov/pubmed/8892926 https://ncbi.nlm.nih.gov/pmc/articles/PMC190876/ https://ncbi.nlm.nih.gov/pubmed/8892927 https://ncbi.nlm.nih.gov/pmc/articles/PMC190877/ https://ncbi.nlm.nih.gov/pubmed/8892928 https://ncbi.nlm.nih.gov/pmc/articles/PMC190878/ https://ncbi.nlm.nih.gov/pubmed/8892929 https://ncbi.nlm.nih.gov/pmc/articles/PMC190879/ https://ncbi.nlm.nih.gov/pubmed/8892930 https://ncbi.nlm.nih.gov/pmc/articles/PMC190880/ https://ncbi.nlm.nih.gov/pubmed/8892931 https://ncbi.nlm.nih.gov/pmc/articles/PMC190881/ https://ncbi.nlm.nih.gov/pubmed/8892932 https://ncbi.nlm.nih.gov/pmc/articles/PMC190882/ https://ncbi.nlm.nih.gov/pubmed/8892933 https://ncbi.nlm.nih.gov/pmc/articles/PMC190883/ https://ncbi.nlm.nih.gov/pubmed/8892934 https://ncbi.nlm.nih.gov/pmc/articles/PMC190884/ https://ncbi.nlm.nih.gov/pubmed/8892935 https://ncbi.nlm.nih.gov/pmc/articles/PMC190885/ https://ncbi.nlm.nih.gov/pubmed/8892936 https://ncbi.nlm.nih.gov/pmc/articles/PMC190886/ https://ncbi.nlm.nih.gov/pubmed/8892937 https://ncbi.nlm.nih.gov/pmc/articles/PMC190887/ https://ncbi.nlm.nih.gov/pubmed/8892938 https://ncbi.nlm.nih.gov/pmc/articles/PMC190888/ https://ncbi.nlm.nih.gov/pubmed/8892939 https://ncbi.nlm.nih.gov/pmc/articles/PMC190889/ https://ncbi.nlm.nih.gov/pubmed/8892940 https://ncbi.nlm.nih.gov/pmc/articles/PMC190890/ https://ncbi.nlm.nih.gov/pubmed/8892941 https://ncbi.nlm.nih.gov/pmc/articles/PMC190891/ https://ncbi.nlm.nih.gov/pubmed/8892942 https://ncbi.nlm.nih.gov/pmc/articles/PMC190892/ https://ncbi.nlm.nih.gov/pubmed/8892943 https://ncbi.nlm.nih.gov/pmc/articles/PMC190893/ https://ncbi.nlm.nih.gov/pubmed/8892944 https://ncbi.nlm.nih.gov/pmc/articles/PMC190894/ https://ncbi.nlm.nih.gov/pubmed/8892945 https://ncbi.nlm.nih.gov/pmc/articles/PMC190895/ https://ncbi.nlm.nih.gov/pubmed/8892946 https://ncbi.nlm.nih.gov/pmc/articles/PMC190896/ https://ncbi.nlm.nih.gov/pubmed/8892947 https://ncbi.nlm.nih.gov/pmc/articles/PMC190897/ https://ncbi.nlm.nih.gov/pubmed/8892948 https://ncbi.nlm.nih.gov/pmc/articles/PMC190898/ https://ncbi.nlm.nih.gov/pubmed/8892949 https://ncbi.nlm.nih.gov/pmc/articles/PMC190899/ https://ncbi.nlm.nih.gov/pubmed/8892950 https://ncbi.nlm.nih.gov/pmc/articles/PMC190900/ https://ncbi.nlm.nih.gov/pubmed/8892951 https://ncbi.nlm.nih.gov/pmc/articles/PMC190901/ https://ncbi.nlm.nih.gov/pubmed/8892952 https://ncbi.nlm.nih.gov/pmc/articles/PMC190902/ https://ncbi.nlm.nih.gov/pubmed/8892953 https://ncbi.nlm.nih.gov/pmc/articles/PMC190903/ https://ncbi.nlm.nih.gov/pubmed/8892954 https://ncbi.nlm.nih.gov/pmc/articles/PMC190904/ https://ncbi.nlm.nih.gov/pubmed/8892955 https://ncbi.nlm.nih.gov/pmc/articles/PMC190905/ https://ncbi.nlm.nih.gov/pubmed/8892956 https://ncbi.nlm.nih.gov/pmc/articles/PMC190906/ https://ncbi.nlm.nih.gov/pubmed/8892957 https://ncbi.nlm.nih.gov/pmc/articles/PMC190907/ https://ncbi.nlm.nih.gov/pubmed/8892958 https://ncbi.nlm.nih.gov/pmc/articles/PMC190908/ https://ncbi.nlm.nih.gov/pubmed/8892959 https://ncbi.nlm.nih.gov/pmc/articles/PMC190909/ https://ncbi.nlm.nih.gov/pubmed/8892960 https://ncbi.nlm.nih.gov/pmc/articles/PMC190910/ https://ncbi.nlm.nih.gov/pubmed/8892961 https://ncbi.nlm.nih.gov/pmc/articles/PMC190911/ https://ncbi.nlm.nih.gov/pubmed/8892962 https://ncbi.nlm.nih.gov/pmc/articles/PMC190912/ https://ncbi.nlm.nih.gov/pubmed/8970944 https://ncbi.nlm.nih.gov/pmc/articles/PMC190913/ https://ncbi.nlm.nih.gov/pubmed/8970945 https://ncbi.nlm.nih.gov/pmc/articles/PMC190914/ https://ncbi.nlm.nih.gov/pubmed/8970946 https://ncbi.nlm.nih.gov/pmc/articles/PMC190915/ https://ncbi.nlm.nih.gov/pubmed/8970947
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الانترنت

Rotavirus VP1 alone specifically binds to the 3' end of viral mRNA, but the interaction is not sufficient to initiate minus-strand synthesis.

الانترنت

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